PROJECTS AND INITIATIVES


Grants

American Cancer Society TheoryLab Collaborative Grant 2021

Understanding estrogen-driven breast tumorigenesis in invasive lobular carcinoma.

Co-PIs: Matt Sikora, Julie Ostrander

https://doi.org/10.53354/pc.gr.151536

CDMRP Breast Cancer Research Program: Breakthrough Award Level 1, Partnering PIs

Estrogen-driven breast tumorigenesis in invasive lobular carcinoma.

Co-PIs: Matt Sikora, Julie Ostrander

W81XWH-22-1-0715; 7/2022 - 7/2025

Meetings and Proceedings

Steroid Hormones and Receptors in Health and Disease: A Research Conference Co-Organized by FASEB and the International Committee on Rapid Responses to Steroid Hormones (RRSH).

IMPACT Meeting Chairs | Zeynep Madak-Erdogan, Dan Frigo
IMPACT Invited Speakers | Matt Sikora, Doug Kojetin, Becca Riggins, Erik Nelson;
IMPACT Session Chairs | Sayee Anakk, Jay Gertz, Christy Hagan, Kristy Brown, Subhamoy Dasgupta, Lindsey Trevino

Barton M, Frigo DE, Madak-Erdogan Z, Mauvais-Jarvis F, Prossnitz ER. | May 25-27, 2021. FASEB J. 2021 Nov;35(11):e21858. | doi: 10.1096/fj.202101228. Access the paper.

ASBMB Annual Meeting 2021 - Signaling Interest Group — Nuclear Receptors

IMPACT Symposia Chairs | Becca Riggins, Doug Kojetin
IMPACT Invited Speakers | Dan Gorelick, Sreejith Nair

https://www.asbmb.org/meetings-events/2021-annual-meeting/networking

Publications and Collaborative Research

WNT4 executes estrogen regulation of cellular metabolism via intracellular activity at the mitochondria.

Sottnik JL, Shackleford MT, Bahnassy S, Madak-Erdogan Z, Riggins RB, Bitler BG, Sikora MJ. | bioRxiv 2022.07.15.499747. | doi: https://doi.org/10.1101/2022.07.15.499747. Access the paper.

Unlocking the Mysteries of Lobular Breast Cancer Biology Needs the Right Combination of Preclinical Models.

Bahnassy S, Sikora MJ, Riggins RB. | Mol Cancer Res. 2022 Jun 3;20(6):837-840. | doi: 10.1158/1541-7786.MCR-22-0018. PMID: 35276005. Access the paper.

The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression.

Baek AE, Krawczynska N, Das Gupta A, Dvoretskiy SV, You S, Park J, Deng YH, Sorrells JE, Smith BP, Ma L, Nelson AT, McDowell HB, Sprenger A, Henn MA, Madak-Erdogan Z, Kong H, Boppart SA, Boppart MD, Nelson ER. | Endocrinology. 2021 Jul 1;162(7):bqab095. | doi: 10.1210/endocr/bqab095. PMID: 33959755; PMCID: PMC8197285. Access the paper.

Endocrine-Disrupting Chemicals and Breast Cancer: Disparities in Exposure and Importance of Research Inclusivity.

Santaliz Casiano A, Lee A, Teteh D, Madak Erdogan Z, Treviño L. | Endocrinology. 2022 May 1;163(5):bqac034. | doi: 10.1210/endocr/bqac034. PMID: 35325096. Access the paper.

Unlocking the Mysteries of Lobular Breast Cancer Biology Needs the Right Combination of Preclinical Models.

Bahnassy S, Sikora MJ, Riggins RB. | Mol Cancer Res. 2022 Mar 11:molcanres.0018.2022. | doi: 10.1158/1541-7786.MCR-22-0018. Epub ahead of print. PMID: 35276005. Access the paper.

TLX, an Orphan Nuclear Receptor With Emerging Roles in Physiology and Disease.

Nelson AT, Wang Y, Nelson ER. | Endocrinology. 2021 Nov 1;162(11):bqab184. | doi: 10.1210/endocr/bqab184. Access the paper.

The Interface of Nuclear and Membrane Steroid Signaling.

Treviño LS, Gorelick DA. | Endocrinology. 2021 Aug 1;162(8):bqab107. | doi: 10.1210/endocr/bqab107. Access the paper.

Making an IMPACT on career development for early- and mid-career faculty.

Sikora MJ, Riggins RB, Madak-Erdogan Z. | Endocrinology. 2021 Jan 7;bqaa247. | doi: 10.1210/endocr/bqaa247. Access the paper.